Genomics Core

The Genomics Core provides access to state-of-the-art instruments and information-intense data for DNA, RNA and microarray analysis. The core specializes in pharmacogenomics, the influence of genes on an individual’s response to medications. 

Our goal is to work closely with researchers to provide quality lab analysis, data and analytical support from project initiation to completion.

Additional Information
Services Provided
Instrumentation
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Contact Information 

Services Provided

  • Initial consultation and study design support
  • Sample size calculation and power analysis
  • Bioinformatics and statistical support
  • Isolation of RNA and DNA
  • RNA and DNA Agilent BioAnalysis
  • Illumina Gene Expression Analysis by BeadArrays for human, mouse and rat
  • Illumina single-nucleotide polymorphism (SNP) and copy-number variation (CNV) analysis by BeadArrays for human
  • Sample preparation for high-throughput sequencing
  • High-throughput sequencing using the Illumina Cluster Station and Genome Analyzer IIx
  • De novo or targeted resequencing
  • mRNA sequencing
  • Tag profiling
  • Small RNA discovery
  • Chromatin Immunoprecipitation (ChIP) Sequencing
  • Sequencing based methylation analysis
  • Custom arrays for gene expression, SNP, etc. with the BeadExpress Reader
  • Whole-genome methylation assays by use of Illumina array-based DNA methylation analysis

Instrumentation

The Core has the following equipment located on the UAMS campus:

Access to the following equipment is available upon request:

  • SpectraMax Microplate Reader
  • Laser Capture Microdissection
  • Applied Biosystems 7900 Real-Time PCR

Request Services

Prior to requesting services, an initial consultation is recommended to discuss study design, sample size calculation, and power analysis. Please contact the technical director for details and appointment times.

Work Order Request

Contact Information

Genomics Core
Winthrop P. Rockefeller Cancer Institute, Room 338
4301 West Markham Street
Little Rock, AR 72205

Susan Kadlubar, Ph.D., Co-Director
Division of Medical Genetics
UAMS College of Medicine
kadlubarsusana@uams.edu
501-526-7957

Charlotte Hobbs, M.D., Ph.D., Co-Director
Department of Pediatrics
UAMS College of Medicine
hobbscharlotte@uams.edu
501-364-5001

Stewart MacLeod, Ph.D., Technical Director
Department of Pediatrics
UAMS College of Medicine
macleodstewartl@uams.edu
501-364-4616